Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

The trials are looking for a drug that does that without lifestyle changes.

There are tons of studies that show that better lifestyle helps, it's just most people can't do it. Not eating trans fats is one small change that will help, that is also easily done.



There are tons of studies that show that better lifestyle helps

Help reduce plaque size? I'd be interested to see those studies!


Help reduce heart attacks, which is what really matters.

Some studies for plaque reduction: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872716/ http://atvb.ahajournals.org/content/19/8/1956.short http://atvb.ahajournals.org/content/15/7/827.short

There were also studies that show better diet stabilizes the plaque, preventing it from causing problems.

If you want to find more studies: https://scholar.google.com/scholar?q=plaque+regression


New insights into the possibility of plaque regression have been elicited by the ASTEROID, REVERSAL, and SATURN studies that utilized intensive statin therapy and demonstrated plaque regression in majority of study patients. However, these trials showed less than 10% regression in overall plaque volume only, which may not explain CV event reduction.

You've changed your claim. First you said a healthy diet will reduce plaque volume, now you say it just helps reduce heart attack rates.

Even the studies you cited only show minimal plaque volume reduction (so small it's questionable if it helps at all) and only with intensive pharmacological therapy.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: