There have been major failures. Several times there were outages at Twitter that were plenty serious enough to be a death knell, or near enough, for a company with less network effect keeping people using them.
I’ve taken FAANG sites down and took it personally when anyone got a 500 error for a minor change. Truth is, no one really cares. You can complain it’s down but who are you going to leave them for? Welcome to running a lean ship. Twitter isn’t hurting