Is slack really that ubiquitous? I wonder what percentage of customers don't use slack or requested something like Teams.

I am not sure why Tailscale is always on Hackernews.

For example, Twingate allows 5 free users and supports more complex use case without requiring a subnet router. They generally have stronger enterprise features as well.

Tailscale is really a winner for simple use cases. For example, these are the steps to access my home server from anywhere in the world with my phone:

1. docker run tailscale/tailscale 2. Use the link provided to login and link my server 3. Download the Tailscale app 4. Login

And if you're using a server OS like Unraid, you don't even need to do the first step; just install it through the GUI. It's widely available and accessible.

TailScale is the HN darling - open source and great for stitching together computers across networks.

Most organisations though are looking at the NetSkope/ZScaler/Perimeter81s of the world and that's where Twingate seems to be picking up the business. It goes beyond the connectivity and has things like non-intrusive device controls which are essential for a lot of places that are in fin tech or have to do SOC2, etc.

Twingate definitely supports complex enterprise use cases for sure but I'll say that somehow it manages to remain super simple to deploy, configure and maintain. I've even got my family on it (let's just say they aren't exactly the most technical folks ever..) so they can access our family photos and other stuff I host at my house (they all live abroad).

My company uses GCP and we found the pricing for their VPN pretty confusing. I worked with someone at my company to research and create one.

Here is a calculator for GCP VPN to hopefully save others the trouble we went through (https://docs.google.com/spreadsheets/d/1LjZ10Bc9Zr7GUhq2UqTD...). Google’s pricing and documentation was so convoluted that we actually caught some mistakes in their own pricing examples. Our full write up is also here: https://www.twingate.com/blog/google-cloud-vpn-pricing/.

Sounds super cool. How many concurrent connections can each connector support?

Good question! At the absolute limit, connectors are CPU-bound, but it's unlikely that you would hit a CPU limit before you exhaust all available file descriptors or network bandwidth unless you're using a very under-powered host.

There's a couple other things that help, too:

1) We allow clustering as many connectors as you'd like to help you scale as usage patterns or application needs change. (This tends to be a big problem with VPN as deploying a new VPN gateway is a fairly heavy lift.)

2) Contrary to VPN deployments, which bottleneck all traffic through a single or small number of VPN gateways, our best practice recommendation is that you deploy as many connectors as you have network segments, which also helps spread out network load across multiple connectors.

Because connectors are quite different to VPN gateways, we wrote up this comparison article, too: https://docs.twingate.com/docs/understanding-access-nodes

There is a startup that runs genetic engineering experiments for you "in the cloud": https://www.arcturus.io/

Not if it is indistinguishable from the real thing and they have no idea as to its origins.

E. coli can be genetically modified to produce fats. Yeast can too. The fat content is just more varied requiring many different yeast clones to be developed for production.

Something like this is already being done. Indiebio just launched in SF and they are doing great work at bringing in pot-doc chemists and biochemists and de-risking their academic work and turning them companies.

Disclaimer, my company Pembient is in the first class.

Ah, that's perfect; the idea is validated. Time to start a competitor in other bio hubs. =)

There are already many well-established biotech accelerators/incubators in Boston (Lab Central, PureTech Ventures, Third Rock Ventures, Flagship Ventures, Atlas Venture, etc.), Seattle (Accelerator Corporation; also in NYC), NYC (Harlem Biospace), and San Diego/Montreal/Vancouver (Inception Sciences).

What do you mean? Their product delay was minimal compared to lockitron (~2years!) and they kept everyone well informed regarding the delay(same can not be said for lockitron). Their refined shipping estimates in light of delays were also spot on. I could not be happier with how Soylent handled things, while I would NEVER purchase anything from lockitron again.

I am an analytical chemist.

Currently I have a company that provides R&D and Manufacture services for salons that want to launch their own label of hair products.

Hello George,

nice to see a chemist, especially one who managed to claim some market share on his own! With hard/wetware, it is not so easy to get your own company going.. and would love to have my own company.

I am a chemist, with a Phd in the field of polymer chemistry, thin films and biomaterials. I did a fair share of small molecule synthesis, polymerizations, simulations and analytics (QPCR, surface plasmons, etc).

PM me, please.